info I collected on HCG | Community Forum

turbo_lucky9.89RPOriginal post

1mo ago

What exactly is Human Chorionic Gonadotropin? Human Chorionic Gonadotropin (HCG) isn't a steroid. It's a naturally produced peptide hormone that, during the early phases of pregnancy, is created by the embryo, and later on, the trophoblast (part of the placenta) takes over. Its primary function is to regulate hormones in a pregnant woman. HCG aids in the proper development of an egg in a woman's ovary and triggers the release of the egg during ovulation. It attaches to the same receptor and is structurally similar to Luteinizing Hormone (LH), which prompts the Leydig cells in male testes to produce testosterone. Due to this resemblance, HCG is utilized to initiate testosterone production in male testes or to induce ovulation in female ovaries. Intended Use of HCG Human Chorionic Gonadotropin is mainly employed as a fertility enhancer. In females, it induces ovulation, while in males, it boosts testosterone levels and sperm production. HCG is also prescribed for young boys whose testicles haven't descended into the scrotum as they should. Additionally, since some cancers release HCG, it can serve as a tumor marker. A positive HCG test result in men (not otherwise using HCG) can indicate testicular cancer or germ cell tumors. HCG in PCT (post cycle treatment) In the realm of bodybuilding pharmacology, HCG is one of the most frequently misunderstood, misapplied, and underappreciated resources available. A bodybuilder who values their health should never compromise well-being for muscle gains. Following any anabolic steroid cycle, the body...

14 replies

dealerdiesel12.18RP

1mo ago

I’m glad you credited giardap at the end. He’s a valuable resource for his research skills. You're right; this is essential reading. While many disapprove of copying and pasting, you did give credit, so +1 for that.

fixerloud11.42RP

1mo ago

If I wanted to read all of this, I could have just done a Google search, right?

slyfox9921.26RP

1mo ago

Copying and pasting can lead to a ban. You might want to take it down and write your own content.

turbo_lucky9.89RP

1mo ago

I hadn't come across this article before, so I figured I’d compile some information and share it; there's more than just what was on that site. If you think I should remove it after adding that it's not my original writing, I'd be happy to do so.

turbo_lucky9.89RP

1mo ago

Yeah... I just thought it would be nice to have it here in the PCT section to make it easier to find.

winter_loud9.57RP

1mo ago

Seems like a copy and paste job. Just make sure to credit all your sources if that's the case.

west_flex9.91RP

1mo ago

At least he isn't asking for advice on his first cycle this time.

bluebell8226.14RP

1mo ago

There is a risk if copyrighted material is included without proper source credit. You must acknowledge any material you copy by linking to the original source.

onyxshadow4.41RP

1mo ago

It might have been wise to note that HCG has a double half-life, so it's better to wait 4-5 days before your next injection. A lot of this post could have been improved if you had sourced your information from medical or scientific sites.

melissax7.32RP

1mo ago

"Preventing testicular atrophy." Smaller balls make my penis look larger though... no offense.

brokerdealer9.48RP

1mo ago

Double half-life?! A 4-5 day dosing schedule is inappropriate for men on AAS, those managing hypogonadism, or kids facing pre-puberty issues, etc. The correct dosing frequency is three times a week. Much of your post would have benefited from information sourced from medical/scientific sites or simply reading the HCG insert when purchasing your kit! People seem to overlook the insert.

onyxshadow4.41RP

1mo ago

Yes, it has a double half-life; HCG is bi-phasic. In fact, the second phase is 2.2 times the length of the first phase, so it's unwise to dose it more than twice a week. It's the frequency, not the amount, that leads to excessive intertesticular aromatization.

brokerdealer9.48RP

1mo ago

No, you’re mixing up a bi-phasic response in testosterone or estrogen production with the half-life of rHCG. In recent studies on rHCG pharmacology, 2.5k IU was administered as a single dose and also as a 5x multi-dose every second day. The difference in peak test plasma levels was minimal, just 34 vs. 43 nmol/l. Estrogen levels were more significant at 194 vs. 295 pmol/l, which you might label as a biphasic response, but it really isn't, and it certainly doesn’t come close to being 2.2 times the levels. The test peaks are visible in the multi-dose at 35-43, showing almost no difference. Naturally, estrogen concentrations rise for a longer duration than serum testosterone, given the various pathways through which estrogen is synthesized. The half-life of HCG itself is approximately 28 hours. Additionally, intratesticular aromatization isn't the only way estrogens are produced during HCG administration. What you're stating is entirely incorrect. I'm happy to share the pharmacology if you're interested. They were published in the Reproductive BioMedicine journal. One thing to consider... during these measurements, 2500 IU was used, which is a dosage meant for fertility treatments, and for ASIH restarts too. For on-cycle HCG usage, 250-500 IU is recommended. PCT usage typically falls in between when HCG was used in bursts during the cycle, and 2-2.5 for around 2-3 weeks only to bridge to PCT where estrogen is strictly managed. With lower doses, the half-life actually decreases to about 23 hours or so.

dustyroad8811.17RP

29d ago

That’s exactly what I wanted to see! I read through everything and never got to the part I was looking for.