High estrogen... how much arimidex?

How are you feeling? If you’re doing well and don’t have any signs of elevated e2, I personally wouldn’t change anything. A 74 e2 level isn’t bad at all, and your free test looks solid. If you want to lower your e2 to around the 50 mark, maybe start with 0.5mg of arimidex once a week, or even every other week. I’d suggest that and then get new labs in 4-6 weeks.

If you’re feeling well and don’t have any clear signs of high estrogen, just leave it as is. But as you increase your dosage, you might encounter issues. I wouldn’t recommend arimidex since it requires frequent dosing to maintain stable levels, and the tablets are 1mg, so you'd need to take about 0.15mg every other day (just a guess). Instead of aiming for a random 500 test, I’d suggest increasing until you notice side effects, then dial it back to a manageable level. I see you’re hesitant to introduce another compound, but if you want to run that much test, aromasin might be a better choice, or consider reaching 500mg total with a bit of mast, like 300mg test and 200mg mast. Just a thought.

My e2 is at 82, and I'm feeling great with no side effects, so I'm not making any changes. Even though our e2 levels are high, so is our testosterone. We both have a 20:1 ratio of test to e2, so if everything feels okay, why change anything?

It really depends on your personal situation. The other responses are right; if you're feeling good, don’t stress too much about that number being high. Not everyone feels symptoms at the same estrogen levels; it varies by individual chemistry. Estrogen plays a crucial role in many processes, including IGF-1 (a key growth factor), organ function, brain health, and even maintaining erections. I find I need arimidex when I exceed a gram of test weekly, usually around 0.5mg three times a week because of its short half-life. But I know that from my own body, not just what blood tests say. I use blood work to monitor silent health indicators like cholesterol, triglycerides, and hematocrit—things that don’t give you direct symptoms like estrogen does. I’m not a fan of aromasin because it has a long half-life, making it tricky to adjust. If you mess up the dosage, it can take a while to stabilize again. A fast-acting option like arimidex is easier to fine-tune. However, if you're feeling good, with no nipple sensitivity, oily skin, and everything's working fine, I'd be content with that.

Thanks for the responses, guys! I'm feeling great, all my other markers are spot on, and my girlfriend is pleased with the morning surprises! Haha. Recently, I've noticed a bit of soreness around my nipples, but maybe I'm just overthinking it. I'm really worried about developing gyno. I'm considering starting with 0.25 mg twice a week and will check my blood work again in 4 weeks.