Effects of Nolvadex on HGH and IGF-1

walkercalm10.26RPOriginal post

1mo ago

I've noticed that my right nipple might be showing signs of very early gyno. I have Nolvadex on hand to tackle this issue. I'm trying to figure out if I should decrease or stop my hgh while using Nolva. From what I've researched, Nolva could potentially lower igf-1 by 20% to 50%, which would obviously lessen the benefits of hgh. However, I came across varying anecdotal evidence online. Looking through forum discussions, it seems that the general opinion is that the effect of Nolva on IGF-1 is minimal compared to AAS and hgh. Right now, I'm taking 12 iu of hgh daily and really enjoy the results. I don't want to cut down or pause my dose, but I also don't want to waste money if it's unnecessary. Any insights would be greatly appreciated. Thanks!

11 replies

wildmoth8.17RP

27d ago

12iu!! What are your igf and z-scores? If all you've really found is anecdotal evidence, it seems to vary from person to person. So get those labs done, start the Nolva, then check the labs again in a few weeks. That’s the only way to know for sure.

raven_14879.64RP

27d ago

HGH does more than just increase serum igf. There’s a distinction between serum igf and local igf (in muscle tissue). High serum igf levels don’t necessarily mean you have high local igf 1 levels. Basically, keep taking it even if you start Nolvadex.

walkercalm10.26RP

25d ago

Thanks a lot!

chrisy5.73RP

25d ago

How do you cope with the fatigue? I'm on 3iu and find myself nodding off multiple times during the day.

walkercalm10.26RP

25d ago

I split my doses into 6 iu in the morning and 6 iu before bed. I don’t feel tired during the day except after big meals. I’m not opposed to taking a long nap when I can. The nighttime dose puts me out and I sleep really well.

lucky_south19.26RP

25d ago

Your body won’t process all of that.

coastwild10.96RP

25d ago

If it’s prolactin-related gyno from the GH, you might be wasting your time. If you were going to use such a high amount of GH, you should already be taking 10mg of Nolva. When your body detects very high igf levels, it "can" trigger the growth of breast tissue cells. A good read is 'The Science of GH' by Havens.

walkercalm10.26RP

25d ago

I use caber, so hopefully prolactin won't be a problem.

coastwild10.96RP

25d ago

Alright cool, yeah I like caber too. Prolactin gyno is a hassle. But to answer your question, you should be fine. The GH temporarily halts your natural production anyway. By taking it morning and night, you're maximizing its effects, just keep an eye on your sugar levels with that dosage. Ceylon cinnamon is really helpful for that. When you stop, you might want to consider semorelin as a bridge between GH cycles. It'll kickstart your natural production quickly so you won't feel a drop. Though it does rebound pretty fast even without the peptide. Some of my best gains have been during sem at night and GH in the mornings.

lucky_south19.26RP

25d ago

12iu is excessive...your body can't utilize that much. Have you had a blood test?

lucky_south19.26RP

25d ago

Prolactin from hgh...? Please explain!!