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blueberrylicious13.68RPOriginal post
There's a fair amount of research showing glass shards from ampoules can be injected. Around 60% of tests find glass fragments, though that rate depends on particle size so the true risk might vary. It didn't bother me much in the past, but since I'm on TRT and expecting a long-term run, I'm thinking about long-term risks. Every paper I've read warns even tiny bits of glass can eventually cause problems — inflammation, scarring, vascular blockages if glass gets into the bloodstream, immune reactions, even death in extreme cases. Rubber has a lower reported rate (roughly 33%), but it still poses risks like ischaemia or allergic responses. Most sources recommend filtering as a mitigation. Filter needles cost a bit, but seem worth it: they filter to 5 microns, so they block most particles (smaller bits could still pass), which appears significant given the reported >60% occurrence. Typical advice is to use a blunt filter needle to draw the solution, then swap to your 25g (or whatever you use) to inject. You could apply the same idea to vials using a sharper filter needle.