Completed 6 Month TRT Frequency/Dosing Trial

wildmoth8.17RPOriginal post

1mo ago

I had my bloodwork done 10 days ago, and Quest took their sweet time getting back to me, but I finally received the results. Last year, I had some low-quality Test C and by January, I was feeling completely drained. I was puzzled until I got my labs done in February. After confirming my low testosterone levels, I found this site and got some Test E. Since I was back at baseline, I decided to experiment with various dosages and frequencies. Here’s the timeline of my 6-month trial for easier reading. Feb 05 2026: T-311 Free T-52 E2-43 - Started Test E at 100mg/week, splitting doses between Tuesday evening and Saturday morning. Mar 24 2026: T-718 Free T-161 E2-82 - Changed to daily injections totaling 105mg/week, with a small dose every morning before breakfast. Jun 10 2026: T-1140 Free T-253 E2-85 - I was going to stop here, but that level seemed too high for TRT. I decided to cut the dosage in half instead of making gradual adjustments for the sake of time, so I went to 52.5mg/week daily in the AM. Aug 03 2026: T-778 Free-168 E2-52 - Interestingly, this half weekly dose (52.5mg) with daily injections gave me higher levels than my previous weekly (100mg) with bi-weekly shots. I realize now my March number was likely at a trough since I had blood drawn on a Tuesday morning without my usual injection, so it's quite possible that peaks were closer to the 1100 I experienced with daily microdosing of 105mg a week. This was something I didn’t consider beforehand. Other markers: Lipids and triglycerides show some interesting trends over these 6 months. Is it related to…

8 replies

mothnitro246.74RP

1mo ago

Regarding hematocrit, I’m not sure about your training or hydration habits, but it might be worth monitoring the basics like staying well-hydrated, doing regular cardio, and avoiding a completely sedentary lifestyle throughout the day. It wasn’t a drastic change for me, but these adjustments seemed to help a little, so I’ve incorporated them into my daily routine.

joan172314.6RP

1mo ago

Nice write-up! I've observed in my own blood tests, and with a client of mine, that daily injections actually lower hematocrit. But as sillygoose mentioned, hematocrit levels are mostly a hydration issue.

wildmoth8.17RP

1mo ago

Yeah, it's always been an issue for me. Even back when I was younger and on active duty, I was in the high 40s. I’ve been discussing this with my doctor for the past 18 months trying to sort it out. I use a CPAP, drink nearly 2 gallons of water a day, and manage to do zone 2 cardio a few times a week. After this last result, I should probably just commit to cardio every day and see if that makes a difference.

wildmoth8.17RP

1mo ago

Honestly, that was one of my main motivations for trying all this. I was really hoping to see my hematocrit decrease. It was shocking and a bit concerning to see that 60! It's trending down now, so I'll keep an eye on it.

joan172314.6RP

1mo ago

There are a couple of blood pressure medications that can help lower hematocrit that you might want to check out.

wildmoth8.17RP

1mo ago

I’ve got some Telmisartan on the way. Let’s see how that goes.

walkerhawk6112RP

1mo ago

Awesome information, man. I'm also prone to high RBC. Have you ever done therapeutic phlebotomy? I have a prescription and go every last Friday of the month to donate blood. It took me about 8 months to get from 55 down to a steady 46-47 off cycle (I always cruise at a minimum of 160mg though). You might want to look into it if you haven't already, dude.

wildmoth8.17RP

1mo ago

I resumed them monthly on July 1st. It worked for me last year, but then my doctor wanted to stop because he found a study suggesting it isn't ideal for secondary polycythemia and can even make your body overproduce RBCs as a rebound effect. You can somewhat lessen that by making smaller donations, but it's just a temporary fix; I'm looking for the underlying cause. It's clear that testosterone injections are influencing it, but my levels are still elevated without the AAS.